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Research date: Thg 10 14, 2025

This systematic review and network meta-analysis evaluated the efficacy of various corticosteroids (dexamethasone, methylprednisolone, hydrocortisone) in preventing postextubation stridor and reintubation in mechanically ventilated adults. The study found that both dexamethasone and methylprednisolone significantly reduced the risk of postextubation stridor and reintubation compared to placebo. Methylprednisolone was identified as the most effective agent for preventing stridor, while dexamethasone was most effective for reducing reintubation risk. The findings suggest that these corticosteroids should be considered for prophylactic use before extubation in this patient population, although further research is needed to confirm these results.

This systematic review and network meta-analysis evaluated the efficacy of various corticosteroids (dexamethasone, methylprednisolone, hydrocortisone) in preventing postextubation stridor and reintubation in mechanically ventilated adults. The study found that both dexamethasone and methylprednisolone significantly reduced the risk of postextubation stridor and reintubation compared to placebo. Methylprednisolone was identified as the most effective agent for preventing stridor, while dexamethasone was most effective for reducing reintubation risk. The findings suggest that these corticosteroids should be considered for prophylactic use before extubation in this patient population, although further research is needed to confirm these results.

The price of petrol in Nigeria has surged to over N600 per litre, with some stations in Lagos and Abuja selling it for an average of N617 per litre. This increase follows the end of fuel subsidy interventions declared by President Bola Tinubu. The price hike has led to increased transportation fares and the cost of goods and services across the country. The Nigerian National Petroleum Company (NNPC) had previously set prices between N480 and N570 per litre, marking a significant increase from the initial price of N169 per litre. With global crude oil prices rising, further increases in petrol prices are expected, and the federal government has yet to implement planned palliative measures to alleviate the impact on citizens.

The price of petrol in Nigeria has surged to over N600 per litre, with some stations in Lagos and Abuja selling it for an average of N617 per litre. This increase follows the end of fuel subsidy interventions declared by President Bola Tinubu. The price hike has led to increased transportation fares and the cost of goods and services across the country. The Nigerian National Petroleum Company (NNPC) had previously set prices between N480 and N570 per litre, marking a significant increase from the initial price of N169 per litre. With global crude oil prices rising, further increases in petrol prices are expected, and the federal government has yet to implement planned palliative measures to alleviate the impact on citizens.