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TrustFinance Global Insights
Mar 23, 2026
2 min read
39

Celldex Therapeutics Inc. (NASDAQ:CLDX) shares increased by 4.6% after Wolfe Research upgraded the stock from Underperform to Outperform. The firm also established a price target of $44.00, signaling renewed confidence in the biopharmaceutical company's future performance.
The upgrade follows a period where the stock's performance did not reflect positive news. However, an analyst noted improved stock reactivity, evidenced by a 24% gain on February 25 after a trial enrollment announcement. Upcoming data for its prurigo treatment, expected in summer 2026, is identified as a significant positive catalyst for the stock.
Wolfe Research highlighted the potential of Celldex's drug, barzolvolimab, which compares favorably against competitors on multiple efficacy measures. The firm views the product as a potential $2 billion-plus asset and considers Celldex severely undervalued. A positive Phase 3 result in the fourth quarter is seen as highly likely and expected to lead to approval.
The combination of improved investor response to news, upcoming data releases, and a strong drug pipeline creates a more comfortable risk-reward profile. Investors will be closely watching for the Phase 3 chronic spontaneous urticaria results expected around the end of the year.
Q: Why did Wolfe Research upgrade Celldex stock?
A: Wolfe Research cited a better catalyst setup for 2026, improved stock reactivity, and a favorable risk-reward profile for its drug barzolvolimab.
Q: What is the new price target for CLDX stock?
A: The new price target set by Wolfe Research is $44.00.
Source: Investing.com

TrustFinance Global Insights
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